April 25, 20024 | No 365
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THINGS WE FIND INTERESTING
We enjoy sharing interesting findings with you and hope they pique your interest too. While we may not always endorse or agree with everything we share, we strive to provide information that can aid you in your pursuit of mental and physical wellness.

Take it from the rats: A junk food diet can cause long-term damage to adolescent brains
Date: April 15, 2024
Source: University of Southern California
A junk food diet during adolescence can cause long-term damage to the brain, according to a study on rats[1]. The researchers found that rats fed a fatty, sugary diet had disrupted acetylcholine signaling in the brain, which is important for encoding and remembering events, similar to episodic memory in humans[1].
The study tracked acetylcholine levels in the brains of rats on a junk food diet and a control group by analyzing their brain responses to memory tests[1]. Post-mortem examination of the rats' brains revealed that the acetylcholine signal was not happening in the animals raised on the fatty, sugary diet[1].
However, the researchers found that the memory damage in rats on the junk food diet could be reversed with medication that induces the release of acetylcholine[1]. Two drugs, PNU-282987 and carbachol, were administered directly to the hippocampus, a brain region that controls memory and is disrupted in Alzheimer's disease, which restored the rats' memory ability[1].
The study suggests that a junk food diet during adolescence, when the brain is undergoing significant development, can have long-lasting negative effects on memory and brain function[1]. The findings highlight the importance of a healthy diet, especially during critical developmental periods, to support optimal brain health[1].
Citations:
[1] https://www.sciencedaily.com/releases/2024/04/240415231853.htm
[2] https://www.sciencedaily.com/about.htm
[3] https://www.sciencedaily.com/news/top/
[4] https://www.sciencedaily.com/news/
[5] https://www.sciencedaily.com/news/top/science/
[6] https://www.sciencedaily.com
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The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.
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